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Skin-adhesive Stretchable Conductors for Wireless Vital Diagnostics

초록/요약

Continuous physiological signal monitoring and diagnosis are crucial for proactive health management and timely interventions. Key challenges include achieving non-toxic adhesion of stretchable conductors to dynamic skin and integration with lightweight, wearable circuits equipped diagnosing algorithms. We propose wireless physiological monitoring with vital diagnosis, featuring octopus-inspired micromembrane structure electrodes that enhance both adhesion and permeability. These stretchable electrodes exhibit a conductivity of over 2,700 S/cm and maintain stretchability up to 1,000%, with minimal degradation after 1,000 cycles of deformation. Adhesion reaches 12 kPa, ensuring durability for over 1,000 attachment-detachment cycles and long-term attachment exceeding 24 hours without skin toxicity. The system, connected to a miniaturized wireless circuit (2.8 g), facilitates real-time, accurate collection of physiological signals, including those from the heart, muscles, eyes, and brain. As proof of concept, ECG signals from real subjects processed with a transfer-learning algorithm achieved over 98% diagnostic accuracy, paving the way for reliable, personalized health monitoring.

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목차

1. Background 1
1.1 Characteristics of electrode type 1
1.2 Selection of conductive materials 2
1.3 Selection of flexible materials 4
1.4 Vital monitoring system configuration 6
2. Introduction 8
2.1 Development of dry electrodes for vital monitoring 8
2.2 Challenges related to adhesion and biocompatibility 8
2.3 Advancements in electrodes through adhesive materials 9
2.4 Unresolved challenges in bio-signal monitoring 11
2.5 Introducing high performance conductors for wireless diagnostics 11
3. Results and discussion 13
3.1 Design of wireless vital diagnostics and skin-compatible stretchable conductors 13
3.2 Electrical and mechanical characterization of stretchable conductors 17
3.3 Bioinspired monolithically interlocked biocompatible adhesive 22
3.4 Wireless ultra-light FPCB for ECG, EMG, EOG, and EEG signal monitoring 27
3.5 ECG-based cardiac health classifier for health assistance 32
4. Conclusions 38
5. Experimental Section 39
5.1 Electrical and mechanical measurement 39
5.2 Impedance measurement 39
5.3 FEM simulation – structure elucidation 39
5.4 Normal and shear adhesion test 40
5.5 FEM simulation – diameter optimization 40
5.6 Fabrication of the M-OIA electrode 40
5.7 Skin irritation test 40
5.8 ECG data preparation and pre-processing 41
5.9 Evaluation and interpretation of the model 41
5.10 Clinical ECG data preparation for healthy subjects 42
6. References 43

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