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Imaging Phenotype of Breast Cancer and Adjacent Parenchyma: Correlation with mRNA Expression of Hormone Receptors, HER2 and TP53

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I. Introduction 1
II. Materials and methods 2
A. Study Participants 2
B. MR Imaging and Image Analysis 2
C. Reverse Transcription of CDNA and Quantitative Real-Time Polymerase Chain Reaction 2
D. Statistical Analysis 3
III. Results 4
IV. Discussion 5
V. List of Tables 7
A. Table 1. Primer sequences used for quantitative real time-PCR 7
B. Table 2. Comparison of mRNA expression in breast cancer according to the imaging
phenotypes 8
C. Table 3. Comparison of mRNA expression in breast parenchyma according to the
mammographic breast density and background parenchymal enhancement on MRI 10
D. Table 4. Correlation analysis for mRNA expression between breast cancer and adjacent
parenchyma 11
VI. List of Figures 12
A. Figure 1. 12
B. Figure 2. 13
C. Figure 3. 13
D. Figure 4. 14
E. Figure 5. 15
VII. References 16

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