변형 가능한 실크 단백질 기반 3차원 광자결정
Deformable and Conformal Silk Hydrogel Inverse Opal
- 주제(키워드) silk fibroin , photonic crystal , photo-cross-linking , ocular prosthesis , intraocular pressure sensor
- 발행기관 아주대학교
- 지도교수 김성환
- 발행년도 2018
- 학위수여년월 2018. 2
- 학위명 석사
- 학과 및 전공 일반대학원 에너지시스템학과
- 실제URI http://www.dcollection.net/handler/ajou/000000026909
- 본문언어 영어
- 저작권 아주대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Applying biopolymer-based nanooptics to biological tissues is an important research theme that will lead the next generation health care industry. The main factors impeding the stable operation of these devices are the large deformation and humid environment of living tissues. Therefore, the nanooptical devices must satisfy deformability, durability, and biocompatibility at the same time. The photonic crystals (PhCs) efficiently manipulate photons at the nanoscale and using reliable biocompatible materials for the PhCs can lead to fascinating bioapplications such as in vivo biosensors and artificial ocular prostheses. In this dissertation, I will present deformable and conformal silk hydrogel inverse opal (SHIO), which can be deformed by mechanical strain, is realized by the UV cross-linking of a liquid stilbene/silk solution The SHIO has excellent biocompatibility and the transparent and elastic hydrogel form is very advantageous as a biosensor. When the SHIO has mechanical deformation such as stretching, bending, and compressing, the lattice constant of the structure changes and the pseudo-photonics band gap (pseudo-PBG) of the SHIO can be stably tuned. Proof-of-concept experiments demonstrate that it can be applied as an intraocular pressure sensor or an ocular prosthesis for better night vision of human.
more목차
1. Introduction and Research Approach 1
1.1 Three-dimensional Photonic Crystals 1
1.2 Introduction of Silk Proteins 2
2. Experimental Procedures 3
2.1 Silk Solution Preparation 3
2.2 Silk Hydrogel Inverse Opal Fabrication Process 4
3. Results and Discussions 12
3.1 Optical Characteristics 12
3.2 Deformation Properties 16
3.3 Applications of the SHIO 21
3.3.1 Ocular Prosthesis 21
3.3.2 Intraocular Pressure Sensor 29
4. Conclusion 31
Reference 32
