고환고정술을 받는 소아 환자에서 미추 차단시 로피바케인과 덱사메타손 병합과 로피바케인 단독 사용의 술 후 진통효과 비교
Analgesic efficacy of caudal dexamethasone combined with ropivacaine in children undergoing orchiopexy
- 발행기관 아주대학교
- 지도교수 문봉기
- 발행년도 2015
- 학위수여년월 2015. 2
- 학위명 박사
- 학과 및 전공 일반대학원 의학과
- 실제URI http://www.dcollection.net/handler/ajou/000000018794
- 본문언어 영어
- 저작권 아주대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Introduction: Epidural administration of dexamethasone might reduce postoperative pain in adults. We evaluated whether a caudal block of 0.1 mg/kg dexamethasone combined with ropivacaine improves analgesic efficacy in children undergoing day-case orchiopexy. Methods: This randomized, double-blind study included 80 children aged 6 months to 5 yr who underwent day-case, unilateral orchiopexy. Patients received either 1.5 ml/kg of 0.15% ropivacaine (Group C) or 1.5 ml/kg of 0.15% ropivacaine in which dexamethasone of 0.1mg/kg was mixed (Group D) for caudal analgesia. Postoperative pain scores, rescue analgesic consumption, and side-effects were evaluated 48 h after operation. Results: Postoperative pain scores at 6 and 24 h post-surgery were significantly lower in Group D than in Group C. Furthermore, the number of subjects who remained pain free up to 48 h after operation was significantly greater in Group D [19 of 38 (50%)] than in Group C [4 of 37 (10.8%); P<0.001]. The number of subjects who received oral analgesic was significantly lower in Group D [11 of 38 (28.9%)] than in Group C [20 of 37 (54.1%); P=0.027]. Time to first oral analgesic administration after surgery was also significantly longer in Group D than in Group C (P=0.014). Adverse events after surgery including vomiting, fever, wound infection, and wound dehiscence were comparable between the two groups. Conclusion: The addition of dexamethasone 0.1 mg/kg to ropivacaine for caudal block can significantly improve analgesic efficacy in children undergoing orchiopexy. Keyword: Caudal anaesthesia, Children, Dexamethasone, Orchiopexy, Postoperative analgesia
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ABSTRACT ··········································································································· ⅰ
TABLE OF CONTENTS ························································································ ⅲ
LIST OF TABLE ···································································································· ⅳ
LIST OF FIGURE ······································································································· v
Ⅰ. INTRODUCTION································································································· 1
Ⅱ. PATIENTS AND METHODS ············································································· 3
Ⅲ. RESULTS ··········································································································· 7
Ⅳ. DISCUSSION ····································································································· 15
Ⅴ. CONCLUSION ··································································································· 21
REFERENCES ········································································································· 22
국문요약 ·················································································································· 27
