토끼 모델을 이용한 미세절골술 및 소파 관절 성형술 후 세포외 기질막 첨가의 유용성
- 발행기관 아주대학교
- 지도교수 민병현
- 발행년도 2010
- 학위수여년월 2010. 2
- 학위명 석사
- 학과 및 전공 일반대학원 의학과
- 실제URI http://www.dcollection.net/handler/ajou/000000010368
- 본문언어 영어
- 저작권 아주대학교 논문은 저작권에 의해 보호받습니다.
목차
ABSTRACT ··················································································································· i
TABLE OF CONTENTS ······················································································ iii
LIST OF FIGURES ···································································································· iv
LIST OF TABLES ····································································································· v
I. INTRODUCTION ···································································································· 1
II. MATERIALS AND METHODS ········································································ 3
A. In vitro ············································································································· 3
1. Animal Models ·························································································· 4
2. Monoclonal Cell Culture and Counting CFUs ·································· 5
B. In vivo ·············································································································· 5
1. Membrane Preparation ············································································ 5
2. Animal Models ·························································································· 5
3. Microfracture and Abrasion Arthroplasty ·········································· 6
4. Gross and Histologic Analysis ····························································· 7
C. Statistical Analysis ························································································ 8
III. RESULTS ············································································································· 9
A. In vitro : Colony Frequency ···································································· 9
B. In vivo : Membrane covering on Chondral defect ····························· 9
C. Gross and Histological Analysis ··························································· 10
1. 4 Weeks Results ····················································································· 10
2. 8 Weeks Results ····················································································· 11
3. 12 Weeks Results ··················································································· 12
Ⅳ. DISCUSSION ······································································································· 16
